cees dekker - An Overview
cees dekker - An Overview
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Human Rad51 filaments on double- and solitary-stranded DNA: correlating frequent and irregular types with recombination purpose.
Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
Our get the job done was immediately adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 published their conclusions on transistors made from single- and multi-walled carbon nanotubes in Used Physics Letters.
This yielded a breakthrough. In only a few months, we ended up in a position to evaluate transport by a person one-walled carbon nanotube. Depending on small-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active investigation lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes ended up genuine quantum wires with quite extensive (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is the fact these components jointly make up a living process. The secret of said daily life, I think, lies while in the interactions, the interplay of Individuals molecules. The massive issue about the origin of daily life is still unanswered. How did we ever evolve from uncomplicated molecules into the particularly complex programs we see now? We have no idea. I would like to operate on these kinds of huge, open up questions.’
2011, very first in vitro https://www.ceesdekker.net measurements of transport across only one biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
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Bulk-surface coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
Mother nature Physics thanks the nameless reviewers for their contribution towards the peer evaluate of the function.
By way of example, we consider the nucleopore complicated, a gateway in between the mobile nucleus along with the cytoplasm. This is an extremely complex procedure and for that reason tough to research in a mobile, so we use biomimetics. We reconstruct holes after which insert individual features with the nucleopore sophisticated to check transportation via it at The one-molecule stage.’
It absolutely was an extremely attention-grabbing time, throughout which I gained a lot of help from Delft College of Technology, in which I used to be a professor at some time, and I commenced quite a few collaborations with molecular biologists. That helped me find out quite a bit.’